Computed Tomography (CT Scanning) is an advanced medical
tool that is not commonly available in veterinary practices. Computed
Tomography is defined as the “presentation of anatomical information
generated by computer synthesis of X-ray data into a video display.” CT
images are made by rotating an X-ray tube around a human or animal while
multiple exposures are recorded on an array of X-ray detectors. The
X-ray beam is narrow, transversing a very small volume or “slice” of
tissue as it moves through an arc of 360º. A slice thickness is
generally 2-5 mm. A computer processes, digitizes, and stores the
electrical signal. A series of images is created which can then be
evaluated by the doctor.
We are pleased to offer in-house CT scanning. The advanced computer
systems allow for scans to be completed in less than 15 minutes in most
cases. CT has much greater resolution than plain radiography or
ultrasound and therefore, is an important tool for diagnosing and
staging cancer. We are often able to detect disease on CT that is not
visible on ultrasound or plain radiographs, thereby improving our
diagnostic accuracy.
CT scan of the lungs of a dog. The arrow points to a tumor in the
lungs that was not visible on plain X-rays
The CT scan on the
previous page shows a slice through the lungs of a canine patient. A
plain radiograph (X-ray) was taken and a large primary lung tumor was
seen. On CT, however, a second tumor was found that was not clearly
visualized on plain X-rays. Therefore, our treatment course was changed
based on this CT. CT scans are used for a wide variety of
applications. Brain tumors, for example, do not show up on routine
radiographs, because the skull blocks our ability to visualize brain
structures on routine radiographs but are seen on CT.
Contrast CT image of the brain of a cat. The arrow points to a large
tumor that had the characteristics of a pituitary macroadenoma. This
tumor was treated with radiation therapy (see patient picture ~ Maxwell
Behringer ~ on back).
How is a CT scan done? CT
scans are performed while patients are under general anesthesia.
Therefore, prior to a scan, blood work is required to be sure the
patient is healthy enough to tolerate general anesthesia. In patients
suspected of having cancer, a chest radiograph is also required prior to
anesthesia. Usually, patients are given a gas anesthetic called
isoflurane. Some patients require an injection of a drug called
“Propofol” to induce anesthesia prior to maintaining anesthesia on gas.
Once under anesthesia,
patients are positioned on the scanner. The images are taken by the CT
scanner and processed by the computer to give us the information we
need. It is usually necessary to give an IV “contrast” agent to help us
image certain structures more precisely. For example, the image of the
brain tumor shown on the previous page is with contrast. It brightens
the image of the tumor aiding in identification.
What are some uses for CT in animals?
There are many instances in veterinary medicine where CT aids in the
diagnosis of tumors and other diseases and helps us determine the extent
of disease present. The use of CT is especially helpful in diagnosing brain and nasal tumors, as these are difficult to impossible to see using plain
radiography. If radiation therapy is used to treat brain or nasal
tumors, a CT is required in order to generate a radiation treatment
plan. Without CT, we would be unsure of the exact location and size of
these tumors. In the case of a suspected primary lung tumor, CT is
extremely helpful in determining the exact location of the mass and if
there is any more disease present in the lungs that may not be visible
with plain radiography. The CT also helps us determine if the lung mass
is operable before we make an attempt at surgery.
The
CT scan performed on this patient was converted to a 3-dimensional
computer based treatment plan for radiation therapy. The use of CT
based planning increases the accuracy of radiation delivery and
decreases exposure to surrounding normal tissues.
Interpretation of CT scans
The
oncologists interpret the scans immediately after the procedure. In
many cases, scans are also sent electronically to Dr. Richard Park, DVM,
PhD, Diplomate, American College of Veterinary Radiology, at Colorado
State University. Dr. Park’s report is available within 1-3 days of the
scanning procedure.
For
patients that are undergoing the CT scan in order to prepare for
radiation therapy, the scans are sent directly to Dr. Sue LaRue at
Colorado State University for radiation treatment planning.
This is a CT scan of a patient diagnosed with osteosarcoma in the
front leg. Several years after treatment, the patient became painful in
the hind limbs. Routine radiographs were normal, so a CT scan was
recommended. The red arrows point to a lesion in the spine that
represented spread of the osteosarcoma. This patient underwent
palliative radiation.
CT
scan (above) of the abdominal cavity of a cat. The measured mass is an
adrenal tumor. With CT we were able to determine that the mass was
adrenal in origin and that there was no other evidence of disease,
making the patient a good candidate for surgery.
Maxwell” Behringer was diagnosed via CT scan with a pituitary
macroadenoma. He underwent a full course of radiation therapy in 2002
and as of 2008 is alive and clinically normal
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